Zelnorm is the trade or brand name for the medicine called Tegaserod.
It is an has been recently licensed and approved for use in 66 countries, excluding the United Kingdom, for treatment of chronic constipation and constipation seen in irritable bowel syndrome.
It has also been reported to be effective in reducing abdominal painand bloating in some IBS sufferers.
For use in the UK, physicians can apply for permission to use it on each individual patient to patient basis.
How Zelnorm Works
Tegaserod belong to a class of drug called 5-HT agonist. What this means is that these class of drug stimulate the effectiveness of a chemical called serotonin.
Specifically, tegaserod has been found to stimulate the serotonin activity in nerves that supply the bowel wall, there by improving peristalsis or contraction and propelling of bowel content downwards.
It also improves secretion of mucus that lubricates the wall of the gut.
When taken orally, it is quickly absorbed, and can attain peak levels in the blood within an hour.
It should be taken on an empty stomach, just before a meal.
Side Effects of Zelnorm
It is has been shown to be safe in most people. Generally, side effects of tegaserod include headache, dizziness, and diarrhoea, cramping abdominal pain, nausea and vomiting.
WHO Should Not Take Zelnorm
If you are pregnant, it is wise to discuss the use of the medication with your doctor, who will weigh the risk of taking it and the benefit with you.
Those with very poor kidney or liver function should also seek advice from their physician.
A few individuals have shown some allergic reaction to this medication and should not continue its use.
Zelnorm comes as a 2mg or 6mg white or marble tablet.
It is manufactured by Novartis Pharmaceuticals.
Zelnorm can only be obtained as a prescription medication for now. It should be stored at room temperature and away from damp.
It is usually prescribed as a 6mg tablet taken twice a day for chronic constipation for up to 6 weeks.
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